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HLA-B ANTIGENS
Descriptors Found:
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DeCS
Descriptor
English
:
HLA-B Antigens
Descriptor
Spanish
:
Antígenos HLA-B
Descriptor
Portuguese
:
Antígenos HLA-B
Synonyms
English
:
HLA-B
Antigens, HLA B
HLA B Antigens
Antigens, HLA-B
Tree Number:
D12.776.395.550.489.500
D12.776.543.550.439.500
D23.050.301.500.100.500
D23.050.301.500.450.380
D23.050.705.552.100.500
D23.050.705.552.450.380
Definition
English
:
Class I human
histocompatibility
(HLA) surface
antigens
encoded by more than 30 detectable
alleles
on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these
antigens
(e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T
lymphocytes.
Indexing Annotation
English
:
general; prefer specifics
History Note
English
:
89
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23670
Unique Identifier:
D015235
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS